RBDs revealed a metabolic stress induced by statins in muscle cells. Published in Stem Cells in October 2015, these results advance the understanding of mechanisms of toxicity of statins, widely used as a cholesterol-lowering agent.

Péric et al, Stem Cells 2015. Cytostatic Effect of Repeated Exposure to Simvastatin: A Mechanism for Chronic Myotoxicity Revealed by the Use of Mesodermal Progenitors Derived from Human Pluripotent Stem Cells